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The same covalent mechanism of action was previously demonstrated for another PAM of GLP-1R (i.e., BETP), showing that in addition to C347, BETP also formed a covalent adduct with C438 in the C terminus 27 that is invisible in the current GLP-1R complex structures

Stat3 inhibition by IFN-b produced in situ by marrow derived mesenchymal stromal cell (MSC) as therapy for primary and metastatic breast cancer

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